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CBL-B-Driven SRC Ubiquitination Intrachain TR-FRET Assay Kit

產(chǎn)品型號(hào)：78820
廠商性質(zhì)：生產(chǎn)廠家
更新時(shí)間：2023-11-12
訪問(wèn) 量：178

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Description

The CBL-B-driven SRC ubiquitination intrachain TR-FRET Assay Kit utilizes a Europium cryptate-labeled Ubiquitin Donor and a Cy5-labeled Ubiquitin Acceptor to complete the TR-FRET pairing. Since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains, this assay does not detect mono-ubiquitination. The FRET-based format requires no time-consuming washing steps, making it especially suitable for HTS applications as well as real-time analyses of polyubiquitination.

Figure 1: CBL-B-driven SRC ubiquitination intrachain TR-FRET Assay Kit schematic.

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Synonyms

E3 ubiquitin-protein ligase CBL-B, Casitas B-lineage lymphoma proto-oncogene b, RING finger protein 56, RING-type E3 ubiquitin transferase CBL-B, SH3-binding protein CBL-B, Signal transduction protein CBL-B, CBLB, RNF56, Nbla00127, Proto-oncogene c-Src

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Inhibition of CBL-B-driven SRC ubiquitination

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CBL-B-Driven SRC Ubiquitination Intrachain TR-FRET Assay Kit

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