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Spike Trimer (S1+S2) (B.1.351, Beta Variant) (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric ...

●Purchase●DescriptionTheSARS-CoV-2SpikeTrimer(S1+S2)(B

  • 產品型號:78174
  • 廠商性質:生產廠家
  • 更新時間:2023-11-12
  • 訪  問  量:168
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The SARS-CoV-2 Spike Trimer (S1+S2) (B.1.351 Variant):ACE2 Inhibitor Screening Colorimetric Assay Kit is designed for screening and profiling inhibitors or neutralizing antibodies of this interaction. The key to this kit is that the SARS-CoV-2 Spike Trimer (S1+S2) (B.1.351 Variant) protein provides a more biologically relevant model than monomeric Spike RBD protein for the investigation of SARS-CoV-2/host cell interaction. Only a few simple steps on a microtiter plate are required for the assay. First, SARS-CoV-2 Spike Trimer (S1+S2) (B.1.351 Variant) is coated on a 96-well plate overnight. Next, the proteins are blocked and pre-incubated with the inhibitor or neutralizing antibody. Upon subsequent incubation with Biotin-ACE2, the plate is treated with Streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce color, which then can be quenched and measured using a UV/Vis microplate reader.

Assay Principle

Assay Principle

Synonyms
Sars-cov-2 B.1.351, 501Y.V2 kit, South Africa variant, B.1.351 inhibitor kit
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