4438ⅹ3亚洲全国最大色,成人性爱视频免费观看,桃花影院电视剧在线播放,精品久久久久久无码专区

熱門搜索: 50072ATAT1, GST-tag Recombinant 40520ATF2, GST-Tag Recombinant 31114GCN5 (727-837), His-tag Recombinant 50074GCN5 (KAT2A), FLAG-tag Recombinant 50071p300 (KAT3B), His-GST-tag Recombinant 11004ACHE, His-Tag Recombinant 50272BCL-2, His-Tag Recombinant 100077BCL2A1, His-Tag Recombinant 100080BCL2L10, His-Tag Recombinant 100091BCL2L2, His-Tag Recombinant 80113Caspase6, His-tag Recombinant 70000Caspase7, His-tag Recombinant 80114Caspase8, His-tag Recombinant 100543GPX4, FLAG-Tag Recombinant 100054MALT1, FLAG-Tag (Mouse) Recombinant 100637MCL-1 His-Tag (Mouse) Recombinant

產(chǎn)品展示/ Product display

您的位置:首頁  /  產(chǎn)品展示  /    /  PDE Assay Kits  /  79558PDE4B1 Assay Kit

PDE4B1 Assay Kit

●Purchase●DescriptionPhosphodiesterases(PDEs)playanimportantroleindynamicregulationofcAMPandcGMPsignaling

  • 產(chǎn)品型號:79558
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時間:2023-11-11
  • 訪  問  量:175
立即咨詢

聯(lián)系電話:

詳細(xì)介紹
Purchase
Description

Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE4 selective inhibitors are currently in clinical trials for the treatment of diseases related to inflammatory disorders. PDE4B1 isoform expression predominates in cortex, however lower expression of PDE4B1 has been observed in the cerebella of subjects with autism when compared with matched controls. The PDE4B1 Assay Kit is designed for identification of inhibitors of PDE4B1 using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE4B1 to the binding agent.

Phosphodiesterases catalyze the hydrolysis of the phosphodiester bond in dye-labeled cyclic monophosphates. Beads selectively bind the phosphate group in the nucleotide product. This increases the size of the nucleotide relative to unreacted cyclic monophosphate. In the polarization assay, dye molecules with absorption transition vectors parallel to the linearly-polarized excitation light are selectively excited. Dyes attached to the rapidly-rotating cyclic monophosphates will obtain random orientations and emit light with low polarization. Dyes attached to the slowly-rotating nucleotide-bead complexes will not have time to reorient and therefore will emit highly polarized light.

The PDE4B1 Assay Kit comes in a convenient 96-well format, with purified PDE4B1 enzyme, fluorescently labeled PDE4B1 substrate (cAMP), binding agent, and PDE assay buffer for 100 enzyme reactions. The key to the PDE4B1 Assay Kit is the specific binding agent. Using this kit, only two simple steps on a microtiter plate are required for PDE4B1 reactions. First, the fluorescently labeled cAMP is incubated with a sample containing PDE4B1 for 1 hour. Second, a binding agent is added to the reaction mix to produce a change in fluorescent polarization that can then be measured using a fluorescence reader equipped for the measurement of fluorescence polarization.

This product has been cited 2 times.

留言詢價

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說明:

  • 驗證碼:

    請輸入計算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7
關(guān)注公眾號

郵箱:infocn@bpsbioscience.com

傳真:

地址:上海靜安區(qū)

Copyright © 2025 BPS Bioscience Inc.版權(quán)所有   備案號:   技術(shù)支持:化工儀器網(wǎng)

TEL:

掃碼加微信
天堂美女久久| 日韩无码视频视频视频视频视频| 日韩欧美综合网站| av熟女| 国产九九精品| 久久AV无码精品午夜福利| 欧羙XX00| 欧美夜夜嗨| 日韩高清在线一区| 爱爱试看| 午夜精品999| www.zhxhs.cn| 久久久久男人精品| 欧美亚洲亚洲精品三区| 色婷亚洲五月综合| 免费人成黄页在线观看国产| 国产又黄又刺激网站| 麻豆aⅴ人妻陈小雨| 91久久久久久久| 青青草av一区二区| 在线看国产精品| 四海影院| 亚洲国产AⅤ精品一区二区的游戏| 日韩AV综合网站| 日本一区二区三区在线观看视频| 亚洲av高清无码在线观看二| 成人国产在线观看高清不卡| 久久国产欧美一区二区免费| 亚洲人人夜夜澡人人爽| 久久五月婷婷影院| 老色鬼网| 日本免费中文字幕| 99久久免费精品视频| 偷拍福利| 三级全黄| 欧美黑香蕉综合视频| MM1313亚洲精品无码| 一区一区三区| 久久偷拍国| 亚洲一区二区三区性色| 日韩永久精品|