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Anti-BCMA-Anti-CD19-Anti-CD3 Trispecific Molecule

●Purchase●DescriptionTheAnti-BCMA-Anti-CD19-Anti-CD3TrispecificMoleculeisengineeredtobindtothreedifferenttargetssimultaneously:1)BCMA

  • 產(chǎn)品型號:100761
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時間:2023-11-10
  • 訪  問  量:236
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Description

The Anti-BCMA-Anti-CD19-Anti-CD3 Trispecific Molecule is engineered to bind to three different targets simultaneously: 1) BCMA, a B cell antigen that is highly expressed by mature B cells and malignant myeloma cells, 2) CD19, a B-cell marker that is a target for many leukemias and lymphomas, and 3) CD3, a T cell receptor activation signal that leads to cytokine secretion. The multi-functionality of this trispecific molecule allows it to bind to BCMA and CD19 on the tumor cell and CD3 on T cells simultaneously, thus bringing T lymphocytes closer to the cancer cells. The binding event targets the tumor while providing co-stimulatory signals that promote T cell expansion and cytotoxicity against BCMA+ and CD19+ cancer cells.

Synonyms
Cluster of Differentiation 19 antibody, B-Lymphocyte Surface Antigen B4 antibody, CVID3, B-cell maturation antigen, TNFRSF17
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